, San Francisco 49ers defeated Arizona Cardinals 38-10 to conclude Week 11 in the NFL. Jimmy Garoppolo threw 4 TDs in the win and Kyler Murray was held out of the Week 11 contest and his replacement Colt McCoy threw for 218 yards and one INT in the loss. Skip Bayless and Shannon Sharpe react to the 49ers win over Cardinals and determine the best team in the NFC.,

San Francisco 49ers defeated Arizona Cardinals 38-10 to conclude Week 11 in the NFL. Jimmy Garoppolo threw 4 TDs in the win and Kyler Murray was held out of the Week 11 contest and his replacement Colt McCoy threw for 218 yards and one INT in the loss. Skip Bayless and Shannon Sharpe react to the 49ers win over Cardinals and determine the best team in the NFC.

5 MINUTES AGO・Skip and Shannon: Undisputed・9:08

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